Saturday 30 January 2016

NOTCH THE ANSWER

Q.All are true regarding Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) except
a. manifest as subcortical dementia of the Binswanger type
b. the notch 3 gene involved
c. symmetric and confluent areas of high signal intensity on the T2 W in the subcortical and periventricular white matter
d. most lesions  in the occipital and parietal lobe
e.patients  typically younger than individuals with subcortical arterial sclerotic encephalopathy.
ANS.---d

Most lesions CADASIL are seen in frontal, temporal, and insular lobes.

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