GADOLINIUM----MR CONTRAST AGENT
Q All are true about Gd DTPA
contrast except
a.chelated to DTPA which allows
safe renal excretion
b.dose is approx. 0.2mg/kg body
weight
c.does not generally cross BBB
d.produce low signal on T1 and
high signal on T2
ANS====d
FACT ABOUT GADOLINIUM
- a heavy metal element having paramagnetic property
- chelated to DTPA which allows safe renal excretion,
- used as MR contrast agent .
- approx.dose is 0.2mg/kg body weight,
- does not generally cross BBB
- mainly positive enhancers that reduce the T1 and T2 relaxation times and increase tissue signal intensity on T1-weighted MR images and have almost no effect on T2-weighted images
- enhance lesions lacking BBB,
- avoided in <6moths of age
- may cause nephrogenic systemic fibrosis in patients with renal insufficiency
- Contraindications for its use are cardiac pacemaker or permanent pacemakers leads,intracranial aneurysm clip,chochlear prostheses etc
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