The apparent diffusion coefficient (ADC) ----?T2 EFFECT

Q.All are true regarding the apparent diffusion coefficient (ADC) except

a. ADC requires sequences with at least two different b-values

b. ADC maps are solely based on differences of tissue diffusion

c. The ADC in the normal brain ranges from 2.94 × 10³mm

d. Areas with a decreased ADC appear dark on ADC maps

e. ADC maps are  dependent on  T2 effects

ANS.---e

ADC maps are solely based on differences of tissue diffusion,

 independent of any T2 effects. The ADC in the normal brain

 ranges from 2.94 × 10³mm² s¹ for CSF to 0.22 × 10³mm² s¹ for

 white matter; grey matter lies in between with a ADC of 0.76 × 

10³mm² s. Areas with a decreased ADC appear dark on ADC 

maps, which is the converse to diffusion-weighted images where 

areas of decreased diffusion appear bright.