Q.All are true regarding imaging of
hepatic hemochromatosis except
a.Dual energy CT ia an accurate
noninvasive means of measuring the liver iron concentration
b.Ferric iron causes extreme
shortening of T1 relaxation time
c.MRI can indicate cause of iron
overload
d.SQUID provides a quantitative
estimate of liver iron
e.Amount of fibrosis can be reduced by
iron depletion
ANS.---b
Ferric iron causes
shortening of both T1 and T2
relaxation time.Although the effect on T1 is moderate ,there is extreme
shortening of the T1 rate.
MRI can indicate cause of iron overload.In patients with
genetic hemochromatosis,there is proportionately less deposition of iron in the
reticuloendothelial system and more deposition in the parenchymal cells of
organs than there is parenteral iron overload.Thus spleen usually exhibits a
low signal intensity in parenteral iron overload and more signal intensity in
genetic hemochromatosis.Pancreas and myocardium show a low signal in genetic
hemochromatosis while theyshow normal signal in iron overload.