Tuesday, 30 December 2025

The seal of signet ring

 

Q1.”The seal of  signet ring” appearance is seen in

a.adenocarcinoma

b.primary mucoid carcinoma

c.carcinoid tumour

d.endometrioma

ANS1.b Primary mucoid carcinoma 



Q2.All feature of signet ring carcinoma of rectum  except

a.grow rapidly

b.early metastase

c.poor prognosis

d.central nucleus

ANS2-d.

In primary mucoid carcinoma ,the mucus lies within the cells

 ,displacing the nucleus to the periphery ,like the seal of a signet ring .


Monday, 29 December 2025

COLORECTAL CARCINOMA

 

Q1 The most common abnormality found in colorectal cancer is

a.mutation in the Wnt signalling pathway

b.mutation in TP53 GENE

c.mutation in TGF -beta gene

d.deleted DCC gene

ANS1.a

The most commonly mutated gene is the APC gene

Q2.Cellular or physiological effects resulting from external or

 environmental factors that switch genes of or on is known as

a.epigenetic alternations

b.hypogenetic alternation

c.hypergenetic alternation

d.random alternation

ANS .a

 

 

Wednesday, 17 December 2025

DELORME OPERATION

 

Q1.Steps of Delorme operation are all except

a.circumferential stripping of rectal mucosa over the length of the prolapse

b.removal of redundant underlying muscles

c.excision of excess mucosa

d.mucosal anastomosis

ANS1.b

The underlying muscle is plicated with a series of sutures ,so that the rectal muscle is concertinaed towards the anal canal .The resulting effect is to reduce the prolapse as plicated ring of muscle above the anal canal

Delorme operation may be preferred in patients with short segment full rectal prolapse



Q2.The procedure of choice in patients presenting with incarcerated and strangulated rectal prolapse is

a.Delorme operation

b.Thiersch operation

c.Altemeier s procedure

d.LVMR

Q2.c

Altemeier procedure is a good alternative perineal procedure to the Delorme operation ,particularly following recurrence .